TY - JOUR AU - Marión, Rosa M AU - Strati, Katerina AU - Li, Han AU - Murga, Matilde AU - Blanco, Raquel AU - Ortega Jimenez, Sagrario AU - Fernandez-Capetillo, Oscar AU - Serrano, Manuel AU - Blasco, MA PY - 2009 DO - 10.1038/nature08287 UR - http://hdl.handle.net/20.500.12105/17689 AB - The reprogramming of differentiated cells to pluripotent cells (induced pluripotent stem (iPS) cells) is known to be an inefficient process. We recently reported that cells with short telomeres cannot be reprogrammed to iPS cells despite their normal... LA - eng PB - Nature Publishing Group KW - Animals KW - Apoptosis KW - Cells, Cultured KW - Cellular Reprogramming KW - Chromosome Aberrations KW - DNA Damage KW - DNA Repair KW - Female KW - Fibroblasts KW - Genomic Instability KW - Humans KW - Male KW - Mice KW - Pluripotent Stem Cells KW - Telomere KW - Tumor Suppressor Protein p53 TI - A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. TY - journal article ER -