TY - GEN AU - Zhang, Nan AU - Schröppel, Bernd AU - Lal, Girdhari AU - Jakubzick, Claudia AU - Mao, Xia AU - Chen, Dan AU - Yin, Na AU - Jessberger, Rolf AU - Ochando, Jordi AU - Ding, Yaozhong AU - Bromberg, Jonathan S PY - 2009 DO - 10.1016/j.immuni.2008.12.022 SN - 1074-7613 UR - http://hdl.handle.net/20.500.12105/8531 AB - To determine the site and mechanism of suppression by regulatory T (Treg) cells, we investigated their migration and function in an islet allograft model. Treg cells first migrated from blood to the inflamed allograft where they were essential for the... LA - eng PB - Elsevier KW - Animals KW - Autoimmunity KW - Cell Movement KW - Cells, Cultured KW - Dendritic Cells KW - Inflammation KW - Islets of Langerhans KW - Lymph Nodes KW - Lymphocyte Subsets KW - Mice KW - Mice, Inbred BALB C KW - Mice, Inbred C57BL KW - Reverse Transcriptase Polymerase Chain Reaction KW - T-Lymphocytes, Regulatory TI - Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response TY - research article ER -