TY  - GEN
AU  - Jung, Su Myung
AU  - Hung, Chien-Min
AU  - Hildebrand, Samuel R
AU  - Sanchez-Gurmaches, Joan
AU  - Martinez-Pastor, Barbara
AU  - Gengatharan, Jivani M
AU  - Wallace, Martina
AU  - Mukhopadhyay, Dimpi
AU  - Martinez Calejman, Camila
AU  - Luciano, Amelia K
AU  - Hsiao, Wen-Yu
AU  - Tang, Yuefeng
AU  - Li, Huawei
AU  - Daniels, Danette L
AU  - Mostoslavsky, Raul
AU  - Metallo, Christian M
AU  - Guertin, David A
PY  - 2019
UR  - https://hdl.handle.net/20.500.12105/26221
AB  - mTORC2 controls glucose and lipid metabolism, but the mechanisms are unclear. Here, we show that conditionally deleting the essential mTORC2 subunit Rictor in murine brown adipocytes inhibits de novo lipid synthesis, promotes lipid catabolism and...
LA  - eng
PB  - Cell Press
KW  - ATGL
KW  - FoxO1
KW  - Rictor
KW  - Sirt6
KW  - UCP1
KW  - acetylation
KW  - adipocyte
KW  - brown adipose tissue
KW  - brown fat
KW  - lipid
KW  - mTOR
KW  - mTORC2
KW  - metabolism
KW  - signaling
TI  - Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
TY  - research article
ER  -