TY  - JOUR
AU  - Ferrara Romeo, Iole
AU  - Martinez Rodriguez, Paula
AU  - Blasco , MA
PY  - 2018
DO  - 10.1371/journal.pone.0204909
SN  - 1932-6203
UR  - http://hdl.handle.net/20.500.12105/6742
AB  - RAP1, a component of the telomere-protective shelterin complex, has been shown to have both telomeric and non-telomeric roles. In the liver, RAP1 is involved in the regulation of metabolic transcriptional programs. RAP1-deficient mice develop obesity...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - PROLIFERATOR-ACTIVATED RECEPTOR
KW  - GENE-EXPRESSION
KW  - TELOMERE DYSFUNCTION
KW  - MAMMALIAN TELOMERES
KW  - METABOLIC SYNDROME
KW  - LIPID HOMEOSTASIS
KW  - PPAR-ALPHA
KW  - LIVER
KW  - CARCINOGENESIS
KW  - HEPATOCARCINOGENESIS
TI  - Mice lacking RAP1 show early onset and higher rates of DEN-induced hepatocellular carcinomas in female mice
TY  - journal article
ER  -