TY - GEN AU - Guerra, Carmen AU - Collado, Manuel AU - Navas, Carolina AU - Schuhmacher, Alberto J AU - Hernández-Porras, Isabel AU - Cañamero, Marta AU - Rodriguez-Justo, Manuel AU - Serrano, Manuel AU - Barbacid, Mariano PY - 2011 DO - 10.1016/j.ccr.2011.05.011 UR - https://hdl.handle.net/20.500.12105/23072 AB - Pancreatic acinar cells of adult mice (?P60) are resistant to transformation by some of the most robust oncogenic insults including expression of K-Ras oncogenes and loss of p16Ink4a/p19Arf or Trp53 tumor suppressors. Yet, these acinar cells yield... LA - eng PB - Cell Press KW - Cellular Senescence KW - Genes, ras KW - Adenocarcinoma KW - Animals KW - Anti-Inflammatory Agents KW - Carcinoma, Pancreatic Ductal KW - Cell Transformation, Neoplastic KW - Cyclin-Dependent Kinase Inhibitor p16 KW - Genes, p53 KW - Humans KW - Mice KW - Pancreas, Exocrine KW - Pancreatic Neoplasms KW - Pancreatitis TI - Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence. TY - research article ER -