TY  - GEN
AU  - Rosigkeit, Sebastian
AU  - Kruchem, Marie
AU  - Thies, Dorothe
AU  - Kreft, Andreas
AU  - Eichler, Emma
AU  - Boegel, Sebastian
AU  - Jansky, Sandrine
AU  - Siegl, Dominik
AU  - Kaps, Leonard
AU  - Pickert, Geethanjali
AU  - Haehnel, Patricia
AU  - Kindler, Thomas
AU  - Hartwig, Udo F
AU  - Guerra, Carmen
AU  - Barbacid, Mariano
AU  - Schuppan, Detlef
AU  - Bockamp, Ernesto
PY  - 2021
DO  - 10.1002/ijc.33756
UR  - http://hdl.handle.net/20.500.12105/19756
AB  - Accumulating evidence suggests that both the nature of oncogenic lesions and the cell-of-origin can strongly influence cancer histopathology, tumor aggressiveness and response to therapy. Although oncogenic Kras expression and loss of Trp53 tumor...
LA  - eng
PB  - Wiley
KW  - Mutation
KW  - Adenocarcinoma
KW  - Animals
KW  - Cell Transformation, Neoplastic
KW  - Disease Progression
KW  - Epithelial Cells
KW  - Gene Expression Regulation, Neoplastic
KW  - Genes, ras
KW  - Humans
KW  - Lung
KW  - Lung Neoplasms
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Tumor Suppressor Protein p53
TI  - Definitive evidence for Club cells as progenitors for mutant Kras/Trp53-deficient lung cancer.
TY  - other
ER  -