TY  - JOUR
AU  - Pucheta-Martínez, Encarna
AU  - Saladino, Giorgio
AU  - Morando, Maria Agnese
AU  - Martinez Torrecuadrada, Jorge Luis
AU  - Lelli, Moreno
AU  - Sutto, Ludovico
AU  - D'Amelio, Nicola
AU  - Gervasio, Francesco Luigi
PY  - 2016
DO  - 10.1038/srep24235
SN  - 2045-2322
UR  - http://hdl.handle.net/20.500.12105/8555
AB  - Phosphorylation of the activation loop is a fundamental step in the activation of most protein kinases. In the case of the Src tyrosine kinase, a prototypical kinase due to its role in cancer and its historic importance, phosphorylation of tyrosine...
LA  - eng
PB  - Nature Publishing Group
KW  - Adenosine Triphosphate
KW  - Allosteric Regulation
KW  - Binding Sites
KW  - Catalytic Domain
KW  - Humans
KW  - Molecular Dynamics Simulation
KW  - Nuclear Magnetic Resonance, Biomolecular
KW  - Phosphorylation
KW  - Thermodynamics
KW  - Tyrosine
KW  - src-Family Kinases
TI  - An Allosteric Cross-Talk Between the Activation Loop and the ATP Binding Site Regulates the Activation of Src Kinase
TY  - journal article
ER  -