TY - GEN AU - Apellániz-Ruiz, María AU - Tejero, Héctor AU - Inglada-Pérez, Lucía AU - Sánchez-Barroso, Lara AU - Gutiérrez-Gutiérrez, Gerardo AU - Calvo, Isabel AU - Castelo, Beatriz AU - Redondo, Andres AU - García-Donás, Jesús AU - Romero-Laorden, Nuria AU - Sereno, María AU - Merino, María AU - Currás-Freixes, María AU - Montero-Conde, Cristina AU - Mancikova, Veronika AU - Åvall-Lundqvist, Elisabeth AU - Green, Henrik AU - Al-Shahrour, Fatima AU - Cascón, Alberto AU - Robledo Batanero, Mercedes AU - Rodríguez-Antona, Cristina PY - 2017 DO - 10.1158/1078-0432.CCR-16-0694 UR - http://hdl.handle.net/20.500.12105/17507 AB - Purpose: Neuropathy is the dose-limiting toxicity of paclitaxel and a major cause for decreased quality of life. Genetic factors have been shown to contribute to paclitaxel neuropathy susceptibility; however, the major causes for interindividual... LA - eng PB - American Association for Cancer Research (AACR) KW - Adult KW - Aged KW - Biomarkers, Pharmacological KW - Breast Neoplasms KW - Female KW - Genetic Association Studies KW - Humans KW - Middle Aged KW - Ovarian Neoplasms KW - Paclitaxel KW - Peripheral Nervous System Diseases KW - Polymorphism, Single Nucleotide KW - Proportional Hazards Models KW - Quality of Life KW - Receptor, EphA5 KW - Receptor, EphA6 KW - Receptor, EphA8 TI - Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy TY - research article ER -