TY - JOUR AU - Lim, R AU - Sugino, T AU - Nolte, H AU - Andrade, J AU - Zimmermann, B AU - Shi, C AU - Doddaballapur, A AU - Ong, Y T AU - Wilhelm, K AU - Fasse, J W D AU - Ernst, A AU - Kaulich, M AU - Husnjak, K AU - Boettger, T AU - Guenther, S AU - Braun, T AU - Krüger, M AU - Benedito, Rui AU - Dikic, I AU - Potente, M PY - 2019 DO - 10.1126/science.aat0778 UR - http://hdl.handle.net/20.500.12105/9685 AB - Notch signaling is a core patterning module for vascular morphogenesis that codetermines the sprouting behavior of endothelial cells (ECs). Tight quantitative and temporal control of Notch activity is essential for vascular development, yet the... LA - eng PB - American Association for the Advancement of Science (AAAS) KW - Animals KW - Endothelium, Vascular KW - HEK293 Cells KW - Human Umbilical Vein Endothelial Cells KW - Humans KW - Mice KW - Mice, Knockout KW - Neovascularization, Physiologic KW - Protein Domains KW - Protein Stability KW - RNA, Small Interfering KW - Receptor, Notch1 KW - Signal Transduction KW - Ubiquitin Thiolesterase KW - Proteolysis TI - Deubiquitinase USP10 regulates Notch signaling in the endothelium TY - journal article ER -