TY - JOUR AU - Pucheta-Martinez, Encarna AU - D'Amelio, Nicola AU - Lelli, Moreno AU - Martinez Torrecuadrada, Jorge Luis AU - Sudol, Marius AU - Saladino, Giorgio AU - Gervasio, Francesco Luigi PY - 2016 DO - 10.1038/srep30293 SN - 2045-2322 UR - http://hdl.handle.net/20.500.12105/8556 AB - WW domains are small domains present in many human proteins with a wide array of functions and acting through the recognition of proline-rich sequences. The WW domain belonging to polyglutamine tract-binding protein 1 (PQBP1) is of particular interest... LA - eng PB - Nature Publishing Group KW - Carrier Proteins KW - Cerebral Palsy KW - DNA-Binding Proteins KW - Humans KW - Intellectual Disability KW - Mental Retardation, X-Linked KW - Molecular Dynamics Simulation KW - Nuclear Magnetic Resonance, Biomolecular KW - Nuclear Proteins KW - Point Mutation KW - Protein Binding KW - Protein Conformation, beta-Strand KW - Protein Folding KW - RNA, Messenger KW - WW Domains TI - Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome TY - journal article ER -