TY - JOUR AU - Iborra, Salvador AU - Martinez-Lopez, Maria AU - Cueto, Francisco J. AU - Conde-Garrosa, Ruth AU - del Fresno, Carlos AU - Izquierdo-Fernandez, Helena Maria AU - Abram, Clare L AU - Mori, Daiki AU - Campos-Martín, Yolanda AU - Reguera, Rosa María AU - Kemp, Benjamin AU - Yamasaki, Sho AU - Robinson, Matthew J AU - Soto, Manuel AU - Lowell, Clifford A AU - Sancho, David PY - 2016 DO - 10.1016/j.immuni.2016.09.012 SN - 1074-7613 UR - http://hdl.handle.net/20.500.12105/9709 AB - C-type lectin receptors sense a diversity of endogenous and exogenous ligands that may trigger differential responses. Here, we have found that human and mouse Mincle bind to a ligand released by Leishmania, a eukaryote parasite that evades an... LA - eng PB - Cell Press KW - Adaptive Immunity KW - Animals KW - CD11c Antigen KW - Cell Differentiation KW - Cell Line, Tumor KW - Dendritic Cells KW - Immunoreceptor Tyrosine-Based Activation Motif KW - Lectins, C-Type KW - Leishmania major KW - Membrane Proteins KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Protein Tyrosine Phosphatase, Non-Receptor Type 6 KW - Receptors, Fc KW - Signal Transduction TI - Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection TY - journal article ER -