TY  - JOUR
AU  - Saiz-Rodríguez, Miriam
AU  - Almenara, Susana
AU  - Navares-Gómez, Marcos
AU  - Ochoa, Dolores
AU  - Román, Manuel
AU  - Zubiaur, Pablo
AU  - Koller, Dora
AU  - Santos, María
AU  - Mejía, Gina
AU  - Borobia, Alberto M
AU  - Rodriguez Antona, Cristina
AU  - Abad-Santos, Francisco
PY  - 2020
DO  - 10.3390/biomedicines8040094
SN  - 2227-9059
UR  - http://hdl.handle.net/20.500.12105/9849
AB  - Several cytochrome P450 (CYP) CYP3A polymorphisms were associated with reduced enzyme function. We aimed to evaluate the influence of these alleles on the pharmacokinetic parameters (PK) of several CYP3A substrates. We included 251 healthy volunteers...
LA  - eng
PB  - Multidisciplinary Digital Publishing Institute (MDPI)
KW  - CYP3A4
KW  - CYP3A5
KW  - pharmacokinetics
TI  - Effect of the Most Relevant CYP3A4 and CYP3A5 Polymorphisms on the Pharmacokinetic Parameters of 10 CYP3A Substrates
TY  - journal article
ER  -