TY - JOUR AU - Moiseeva, Victoria AU - Cisneros, Andrés AU - Sica, Valentina AU - Deryagin, Oleg AU - Lai, Yiwei AU - Jung, Sascha AU - Andrés, Eva AU - An, Juan AU - Segalés, Jessica AU - Ortet, Laura AU - Lukesova, Vera AU - Volpe, Giacomo AU - Benguria, Alberto AU - Dopazo, Ana AU - Benitah, Salvador Aznar AU - Urano, Yasuteru AU - Del Sol, Antonio AU - Esteban, Miguel A AU - Ohkawa, Yasuyuki AU - Serrano, Antonio L AU - Perdiguero, Eusebio AU - Munoz-Canoves, Pura PY - 2023 DO - 10.1038/s41586-022-05535-x UR - http://hdl.handle.net/20.500.12105/16470 AB - Tissue regeneration requires coordination between resident stem cells and local niche cells1,2. Here we identify that senescent cells are integral components of the skeletal muscle regenerative niche that repress regeneration at all stages of life.... LA - eng PB - Nature Publishing Group KW - Aging KW - Cellular Senescence KW - Inflammation KW - Muscle, Skeletal KW - Regeneration KW - Stem Cell Niche KW - Aged KW - Animals KW - Humans KW - Mice KW - Stem Cells KW - Fibrosis KW - Transcriptome KW - Chromatin KW - Geroscience TI - Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration. TY - journal article ER -