TY - GEN AU - Oliva-Martinez, Jose Luis AU - Caino, M Cecilia AU - Senderowicz, Adrian M AU - Kazanietz, Marcelo G PY - 2008 DO - 10.1074/jbc.M707576200 SN - 0021-9258 UR - http://hdl.handle.net/20.500.12105/12531 AB - Protein kinase C (PKC) has been widely implicated in positive and negative control of cell proliferation. We have recently shown that treatment of non-small cell lung cancer (NSCLC) cells with phorbol 12-myristate 13-acetate (PMA) during G1 phase... LA - eng PB - American Society for Biochemistry and Molecular Biology (ASBMB) KW - Cellular Senescence KW - S Phase KW - Carcinogens KW - Carcinoma, Non-Small-Cell Lung KW - Cell Cycle KW - Cell Line, Tumor KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Enzyme Activation KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Isoenzymes KW - Protein Kinase C-alpha KW - Protein Kinase C-delta KW - Telomerase KW - Tetradecanoylphorbol Acetate KW - Up-Regulation KW - beta-Galactosidase TI - S-Phase-specific activation of PKC alpha induces senescence in non-small cell lung cancer cells TY - research article ER -