TY - JOUR AU - Villatoro, Alicia AU - Cuminetti, Vincent AU - Bernal, Aurora AU - Torroja, Carlos AU - Cossío, Itziar AU - Benguría, Alberto AU - Ferré, Marc AU - Konieczny, Joanna AU - Vázquez, Enrique AU - Rubio, Andrea AU - Utnes, Peter AU - Tello, Almudena AU - You, Xiaona AU - Fenton, Christopher G AU - Paulssen, Ruth H AU - Zhang, Jing AU - Sanchez-Cabo, Fatima AU - Dopazo, Ana AU - Vik, Anders AU - Anderssen, Endre AU - Hidalgo, Andrés AU - Arranz, Lorena PY - 2023 DO - 10.1038/s41467-022-35700-9 UR - http://hdl.handle.net/20.500.12105/16636 AB - Here we explored the role of interleukin-1β (IL-1β) repressor cytokine, IL-1 receptor antagonist (IL-1rn), in both healthy and abnormal hematopoiesis. Low IL-1RN is frequent in acute myeloid leukemia (AML) patients and represents a prognostic marker... LA - eng PB - Nature Publishing Group KW - Receptors, Interleukin-1 KW - Leukemia, Myeloid, Acute KW - Humans KW - Bone Marrow KW - Cell Proliferation KW - Antigens, CD34 TI - Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation. TY - journal article ER -