TY - GEN AU - Gonzalez-Jimenez, Irene AU - Lucio, Jose AU - Roldán, Alejandra AU - Alcazar-Fuoli, Laura AU - Mellado, Emilia PY - 2021 DO - 10.3390/molecules26195975 UR - http://hdl.handle.net/20.500.12105/14256 AB - Invasive aspergillosis, mainly caused by Aspergillus fumigatus, can lead to severe clinical outcomes in immunocompromised individuals. Antifungal treatment, based on the use of azoles, is crucial to increase survival rates. However, the recent... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - Aspergillus fumigatus KW - Azole resistance mechanisms KW - Cyp51A KW - Hmg1 KW - Hmg2 TI - Are Point Mutations in HMG-CoA Reductases (Hmg1 and Hmg2) a Step towards Azole Resistance in Aspergillus fumigatus? TY - research article ER -