TY - JOUR AU - Kuchnio, Anna AU - Moens, Stijn AU - Bruning, Ulrike AU - Kuchnio, Karol AU - Cruys, Bert AU - Thienpont, Bernard AU - Broux, Michaël AU - Ungureanu, Andreea Alexandra AU - Leite de Oliveira, Rodrigo AU - Bruyère, Françoise AU - Cuervo, Henar AU - Manderveld, Ann AU - Carton, An AU - Hernandez-Fernaud, Juan Ramon AU - Zanivan, Sara AU - Bartic, Carmen AU - Foidart, Jean-Michel AU - Noel, Agnes AU - Vinckier, Stefan AU - Lambrechts, Diether AU - Dewerchin, Mieke AU - Mazzone, Massimiliano AU - Carmeliet, Peter PY - 2015 DO - 10.1016/j.celrep.2015.07.010 UR - http://hdl.handle.net/20.500.12105/17215 AB - Several questions about the role of the oxygen sensor prolyl-hydroxylase 2 (PHD2) in cancer have not been addressed. First, the role of PHD2 in metastasis has not been studied in a spontaneous tumor model. Here, we show that global PHD2... LA - eng PB - Cell Press KW - Animals KW - Cell Line, Tumor KW - Female KW - Fibroblasts KW - Humans KW - Hypoxia-Inducible Factor-Proline Dioxygenases KW - Immunoblotting KW - Immunohistochemistry KW - Male KW - Mice KW - Models, Biological KW - Neoplasm Metastasis KW - Neoplasms KW - Reverse Transcriptase Polymerase Chain Reaction TI - The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts. TY - journal article ER -