TY - GEN AU - Ledesma, Juan AU - Pozo Sanchez, Francisco AU - Pérez-Ruiz, Mercedes AU - Navarro, José María AU - Piñeiro, Luis AU - Montes, Milagros AU - Pérez Castro, Sonia AU - Suárez Fernández, Jonathan AU - García Costa, Juan AU - Fernández, Mirian AU - Galán, Juan Carlos AU - Cuevas, Maria Teresa AU - Casas Flecha, Inmaculada AU - Perez-Breña, Pilar AU - Spanish Influenza Surveillance System (SISS) AU - Jimenez-Jorge, Silvia PY - 2011 DO - 10.1016/j.jcv.2011.01.020 SN - 1386-6532 UR - https://hdl.handle.net/20.500.12105/26142 AB - Background: A change of aspartic acid (D) to glycine (G) at position 222 in the haemagglutinin (HA) protein of pandemic influenza A (H1N1) 2009 viruses was described in Norway on November 2009 with considerable frequency in fatal and severe cases.... LA - eng PB - Elsevier KW - Pandemic influenza A (H1N1) 2009 virus KW - Haemagglutinin sequencing KW - D222G substitution KW - Severe respiratory infection KW - Adolescent KW - Adult KW - Amino Acid Substitution KW - Antiviral Agents KW - Female KW - Hemagglutinin Glycoproteins, Influenza Virus KW - Humans KW - Influenza A Virus, H1N1 Subtype KW - Influenza, Human KW - Male KW - Middle Aged KW - Mutation KW - Oseltamivir KW - Pandemics KW - Sequence Analysis, DNA KW - Spain TI - Substitutions in position 222 of haemagglutinin of pandemic influenza A (H1N1) 2009 viruses in Spain TY - research article ER -