TY - GEN AU - de los Santos-Jiménez, Juan AU - Campos-Sandoval, José A. AU - Márquez-Torres, Clara AU - Urbano-Polo, Nieves AU - Brøndegaard, David AU - Martín-Rufián, Mercedes AU - Lobo, Carolina AU - Peñalver, Ana AU - Gómez-García, María C. AU - Martín-Campos, Janet AU - Cardona, Carolina AU - Castilla, Laura AU - da Costa Souza, Felipe AU - Cheng, Tzuling AU - Segura, Juan A. AU - Alonso, Francisco J. AU - Curi, Rui AU - Colquhoun, Alison AU - DeBerardinis, Ralph J. AU - Márquez, Javier AU - Matés, José M. PY - 2021 DO - 10.1186/s12929-021-00712-y SN - 1021-7770 UR - http://hdl.handle.net/20.500.12105/18264 AB - Background: Glutaminase isoenzymes GLS and GLS2 play apparently opposing roles in cancer: GLS acts as an oncoprotein, while GLS2 (GAB isoform) has context specific tumour suppressive activity. Some microRNAs (miRNAs) have been implicated in... LA - eng PB - BioMed Central (BMC) KW - Antioxidant enzymes KW - Cancer KW - Glioblastoma KW - Glutaminase KW - MicroRNA KW - Oxidative stress KW - Cell line KW - Lipid peroxidation KW - Glutathione KW - Isoenzymes KW - Antioxidantes KW - Enzimas KW - Neoplasias KW - Glutaminasa KW - MicroARNs KW - Estrés oxidativo KW - Línea celular KW - Peroxidación de lípido KW - Glutatión KW - Isoenzimas KW - Cell Line, Tumor KW - Down-Regulation KW - Glioblastoma KW - Glutaminase KW - Humans KW - Isoenzymes KW - MicroRNAs KW - Up-Regulation KW - Gene Expression Regulation, Neoplastic KW - Oxidative Stress KW - Glutathione Reductase KW - Lipid Peroxidation KW - Protein Carbonylation KW - Antioxidants KW - Neoplasms KW - Protein Isoforms KW - Cell Proliferation TI - Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells TY - research article ER -