TY - GEN AU - Sanchez, Agustin AU - Setién, F AU - Martinez, Natalia AU - Oliva-Martinez, Jose Luis AU - Herranz, M AU - Fraga, M-F AU - Alaminos, M AU - Esteller, M AU - Rojas-Cabañeros, Jose Maria PY - 2008 DO - 10.1038/onc.2008.129 SN - 0950-9232 UR - https://hdl.handle.net/20.500.12105/26130 AB - Spry2 has been characterized as a negative regulator of the extracellular-regulated kinase (ERK) pathway. In this study we analysed whether epigenetic alterations of hSpry2 promoter occur in human lymphoid/hematopoietic malignancies. Our results... LA - eng PB - Nature Publishing Group KW - hSpry2 KW - Epigenetic KW - Lymphomas KW - B cells KW - Suppressor gene KW - Animals KW - Epigenesis, Genetic KW - Extracellular Signal-Regulated MAP Kinases KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - Lymphoma, B-Cell KW - Membrane Proteins KW - Mice KW - Mice, Nude KW - Protein Kinase Inhibitors KW - Tetradecanoylphorbol Acetate TI - Epigenetic inactivation of the ERK inhibitor Spry2 in B-cell diffuse lymphomas TY - research article ER -