TY - JOUR AU - Thornton, Tina M. AU - Delgado, Pilar AU - Chen, Liang AU - Salas, Beatriz AU - Krementsov, Dimitry AU - Fernandez, Miriam AU - Vernia, Santiago AU - Davis, Roger J. AU - Heimann, Ruth AU - Teuscher, Cory AU - Krangel, Michael S. AU - Ramiro, Almudena R AU - Rincon, Mercedes PY - 2016 DO - 10.1038/ncomms10553 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/5252 AB - Variable, diversity and joining (V(D)J) recombination and immunoglobulin class switch recombination (CSR) are key processes in adaptive immune responses that naturally generate DNA double-strand breaks (DSBs) and trigger a DNA repair response. It is... LA - eng PB - Nature Publishing Group KW - GLYCOGEN-SYNTHASE KINASE-3-BETA KW - CLASS SWITCH RECOMBINATION KW - T-CELL DEVELOPMENT KW - V(D)J RECOMBINATION KW - DAMAGE RESPONSE KW - HISTONE H2AX KW - P38 MAPK KW - KINASE KW - MCL-1 KW - DEATH TI - Inactivation of nuclear GSK3 beta by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response TY - journal article ER -