TY  - JOUR
AU  - Oldrini, Barbara
AU  - Curiel Garcia, Alvaro
AU  - Almeida Marques, Carolina
AU  - Matia Garcia, Veronica
AU  - Uluçkan, Azge
AU  - Graña Castro, Osvaldo
AU  - Torres-Ruiz, Raul
AU  - Rodriguez Perales, Sandra
AU  - Huse, Jason T
AU  - Squatrito, Massimo
PY  - 2018
DO  - 10.1038/s41467-018-03731-w
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/6507
AB  - To accurately recapitulate the heterogeneity of human diseases, animal models require to recreate multiple complex genetic alterations. Here, we combine the RCAS-TVA system with the CRISPR-Cas9 genome editing tools for precise modeling of human...
LA  - eng
PB  - Nature Publishing Group
KW  - IN-VIVO
KW  - CHROMOSOMAL REARRANGEMENTS
KW  - ACQUIRED-RESISTANCE
KW  - COLORECTAL-CANCER
KW  - TARGETED THERAPY
KW  - NERVOUS-SYSTEM
KW  - GENE-TRANSFER
KW  - LUNG-CANCER
KW  - MOUSE-LIVER
KW  - GLIOBLASTOMA
TI  - Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling
TY  - journal article
ER  -