TY  - JOUR
AU  - López-Contreras, Andres J
AU  - Gutierrez-Martinez, Paula
AU  - Specks, Julia
AU  - Rodrigo-Perez, Sara
AU  - Fernandez-Capetillo, Oscar
PY  - 2012
DO  - 10.1084/jem.20112147
UR  - http://hdl.handle.net/20.500.12105/17683
AB  - Replicative stress (RS) is a type of endogenous DNA damage that cells suffer every time they duplicate their genomes, and which is further boosted by oncogenes. In mammals, the RS response (RSR) is coordinated by ATR and Chk1 kinases. We sought to...
LA  - eng
PB  - Rockefeller University Press
KW  - Alleles
KW  - Animals
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Cell Cycle Proteins
KW  - Cell Transformation, Neoplastic
KW  - Checkpoint Kinase 1
KW  - DNA Damage
KW  - DNA-Binding Proteins
KW  - Dwarfism
KW  - Facies
KW  - Gene Dosage
KW  - Mice
KW  - Mice, Knockout
KW  - Mice, Mutant Strains
KW  - Mice, Transgenic
KW  - Microcephaly
KW  - Oncogenes
KW  - Protein Kinases
KW  - Protein Serine-Threonine Kinases
KW  - Tumor Suppressor Proteins
TI  - An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation.
TY  - journal article
ER  -