TY  - JOUR
AU  - Bosso, Giuseppe
AU  - Lanuza-Gracia, Pablo
AU  - Piñeiro-Hermida, Sergio
AU  - Yilmaz, Merve
AU  - Serrano, Rosa
AU  - Blasco, MA
PY  - 2022
DO  - 10.1038/s41419-022-04597-z
UR  - http://hdl.handle.net/20.500.12105/19027
AB  - The BRAF gene is frequently mutated in cancer. The most common genetic mutation is a single nucleotide transition which gives rise to a constitutively active BRAF kinase (BRAFV600E) which in turn sustains continuous cell proliferation. The study of...
LA  - eng
PB  - Nature Publishing Group
KW  - Adenoma
KW  - Proto-Oncogene Proteins B-raf
KW  - Animals
KW  - Carcinogenesis
KW  - Cell Line, Tumor
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - Disease Models, Animal
KW  - Mice
KW  - Mutation
KW  - Oncogenes
KW  - Tumor Suppressor Protein p53
TI  - Early differential responses elicited by BRAFV600E in adult mouse models.
TY  - journal article
ER  -