TY - JOUR AU - Raza, Qanber AU - Nadeem, Taliha AU - Youn, Seock-Won AU - Swaminathan, Bhairavi AU - Gupta, Ahana AU - Sargis, Timothy AU - Du, Jing AU - Cuervo, Henar AU - Eichmann, Anne AU - Ackerman, Susan L AU - Naiche, L A AU - Kitajewski, Jan PY - 2024 DO - 10.1038/s41598-024-64375-z UR - http://hdl.handle.net/20.500.12105/20208 AB - Notch signaling guides vascular development and function by regulating diverse endothelial cell behaviors, including migration, proliferation, vascular density, endothelial junctions, and polarization in response to flow. Notch proteins form... LA - eng PB - Nature Publishing Group KW - Netrin Receptors KW - Receptors, Notch KW - Cell Proliferation KW - Signal Transduction KW - Cell Movement KW - Endothelial Cells KW - Retina KW - Animals KW - Mice KW - Humans KW - Retinal Vessels KW - Neovascularization, Physiologic TI - Notch signaling regulates UNC5B to suppress endothelial proliferation, migration, junction activity, and retinal plexus branching. TY - journal article ER -