TY - GEN AU - Mutz, Cornelia N AU - Schwentner, Raphaela AU - Aryee, Dave N T AU - Bouchard, Eric D J AU - Mejia, Edgard M AU - Hatch, Grant M AU - Kauer, Maximilian O AU - Katschnig, Anna M AU - Ban, Jozef AU - Garten, Antje AU - Alonso, Javier AU - Banerji, Versha AU - Kovar, Heinrich PY - 2017 DO - 10.18632/oncotarget.14976 SN - 1949-2553 UR - http://hdl.handle.net/20.500.12105/9613 AB - Ewing sarcoma (EwS) is the second most common bone cancer in children and adolescents with a high metastatic potential. EwS development is driven by a specific chromosomal translocation resulting in the generation of a chimeric EWS-ETS transcription... LA - eng PB - Impact Journals KW - EWS-FLI1 KW - Ewing sarcoma KW - FK866 KW - NAD KW - NAMPT KW - Acrylamides KW - Bone Neoplasms KW - Cell Line, Tumor KW - Cytokines KW - Drug Resistance, Neoplasm KW - Enzyme Inhibitors KW - HeLa Cells KW - Humans KW - NAD KW - Nicotinamide Phosphoribosyltransferase KW - Oncogene Proteins, Fusion KW - Piperidines KW - Proto-Oncogene Protein c-fli-1 KW - RNA-Binding Protein EWS KW - Sarcoma, Ewing TI - EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells TY - research article ER -