TY - GEN AU - Jacobs, Maaike M E AU - Maas, Rianne J F AU - Jonkman, Inge AU - Negishi, Yutaka AU - Tielemans Zamora, Willem AU - Yanginlar, Cansu AU - van Heck, Julia AU - Matzaraki, Vasiliki AU - Martens, Joost H A AU - Baltissen, Marijke AU - Vermeulen, Michiel AU - Morla-Folch, Judit AU - Ranzenigo, Anna AU - Wang, William AU - Umali, Martin AU - Ochando, Jordi AU - van der Vlag, Johan AU - Hilbrands, Luuk B AU - Joosten, Leo A B AU - Netea, Mihai G AU - Mulder, Willem J M AU - van Leent, Mandy M T AU - Mhlanga, Musa M AU - Teunissen, Abraham J P AU - Rother, Nils AU - Duivenvoorden, Raphaël PY - 2024 DO - 10.1016/j.celrep.2024.114664 UR - https://hdl.handle.net/20.500.12105/26569 AB - Trained immunity is characterized by histone modifications and metabolic changes in innate immune cells following exposure to inflammatory signals, leading to heightened responsiveness to secondary stimuli. Although our understanding of the molecular... LA - eng PB - Cell Press KW - CD40-CD40L KW - CP: Immunology KW - T cells KW - Innate immunity KW - Monocytes KW - Nanobiologics KW - Trained immunity KW - Animals KW - CD40 Antigens KW - Heart Transplantation KW - Humans KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Signal Transduction KW - T-Lymphocytes KW - TNF Receptor-Associated Factor 6 KW - Trained Immunity TI - Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling TY - research article ER -