TY - GEN AU - Wadelius, Mia AU - Eriksson, Niclas AU - Kreutz, Reinhold AU - Bondon-Guitton, Emmanuelle AU - Ibañez, Luisa AU - Carvajal, Alfonso AU - Lucena, M Isabel AU - Sancho Ponce, Esther AU - Molokhia, Mariam AU - Martin, Javier AU - Axelsson, Tomas AU - Kohnke, Hugo AU - Yue, Qun-Ying AU - Magnusson, Patrik K E AU - Bengtsson, Mats AU - Hallberg, Pär AU - EuDAC PY - 2017 DO - 10.1002/cpt.805 UR - http://hdl.handle.net/20.500.12105/17335 AB - Agranulocytosis is a serious, although rare, adverse reaction to sulfasalazine, which is used to treat inflammatory joint and bowel disease. We performed a genome-wide association study comprising 9,380,034 polymorphisms and 180 HLA alleles in 36... LA - eng KW - Adult KW - Aged KW - Agranulocytosis KW - Alleles KW - Case-Control Studies KW - Female KW - Genome-Wide Association Study KW - Genotype KW - HLA-B Antigens KW - HLA-DQ beta-Chains KW - Haplotypes KW - Humans KW - Male KW - Middle Aged KW - Sulfasalazine TI - Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus. TY - research article ER -