TY - JOUR AU - Sanchez-Aguilera, Abel AU - Mendez-Ferrer, Simon PY - 2017 DO - 10.1007/s00018-016-2306-y SN - 1420-682X UR - http://hdl.handle.net/20.500.12105/5165 AB - Research in the last decade has shown that hematopoietic stem cells (HSCs) interact with and are modulated by a complex multicellular microenvironment in the bone marrow, which includes both the HSC progeny and multiple non-hematopoietic cell types.... LA - eng PB - Springer KW - Hematopoietic stem cell KW - Stem cell niche KW - Bone marrow microenvironment KW - Leukemia KW - Leukemia stem cell KW - BONE-MARROW NICHE KW - CHRONIC MYELOGENOUS LEUKEMIA KW - MESENCHYMAL STROMAL CELLS KW - ACUTE MYELOID-LEUKEMIA KW - IN-VIVO KW - PROGENITOR CELLS KW - ENDOTHELIAL NICHES KW - SELF-RENEWAL KW - MOUSE MODEL KW - MICROENVIRONMENT TI - The hematopoietic stem-cell niche in health and leukemia TY - journal article ER -