TY - GEN AU - Rodriguez-Nunez, Olga AU - Periáñez Párraga, Leonor AU - Oliver, Antonio AU - Munita, Jose M AU - Bote, Anna AU - Gasch, Oriol AU - Nuvials, Xavier AU - Dinh, Aurelien AU - Shaw, Robert AU - Lomas, Jose M AU - Torres, Vicente AU - Caston, Juanjo AU - Araos, Rafael AU - Abbo, Lilian M AU - Rakita, Robert AU - Perez, Federico AU - Aitken, Samuel L AU - Arias, Cesar A AU - Luisa Martin-Pena, M AU - Colomar Ferra, Maria Asuncion AU - Belen Nunez, M AU - Mensa, Josep AU - Antonio Martinez, Jose AU - Soriano, Alex PY - 2019 DO - 10.1093/ofid/ofz416 SN - 2328-8957 UR - https://hdl.handle.net/20.500.12105/22787 AB - Background. Ceftolozane/tazobactam (C/T) efficacy and safety in ventilator-associated pneumonia (VAP) is being evaluated at a double dose by several trials. This dosing is based on a pharmacokinetic (PK) model that demonstrated that 3 g q8h achieved... LA - eng PB - Oxford University Press KW - Ceftolozane/tazobactam KW - Multidrug-resistant KW - Pneumonia KW - Pseudomonas aeruginosa KW - Tracheobronchitis TI - Higher MICs (> 2 mg/L) Predict 30-Day Mortality in Patients With Lower Respiratory Tract Infections Caused by Multidrug- and Extensively Drug-Resistant Pseudomonas aeruginosa Treated With Ceftolozane/Tazobactam TY - research article ER -