TY  - JOUR
AU  - Ahuja, Akshay K
AU  - Jodkowska, Karolina
AU  - Teloni, Federico
AU  - Bizard, Anna H
AU  - Zellweger, Ralph
AU  - Herrador, Raquel
AU  - Ortega Jimenez, Sagrario
AU  - Hickson, Ian D
AU  - Altmeyer, Matthias
AU  - Mendez, Juan
AU  - Lopes, Massimo
PY  - 2016
DO  - 10.1038/ncomms10660
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/7866
AB  - Embryonic stem cells (ESCs) represent a transient biological state, where pluripotency is coupled with fast proliferation. ESCs display a constitutively active DNA damage response (DDR), but its molecular determinants have remained elusive. Here we...
LA  - eng
PB  - Nature Publishing Group
KW  - Animals
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Blastocyst
KW  - Blotting, Western
KW  - Chromatin
KW  - Chromosomal Proteins, Non-Histone
KW  - DNA, Single-Stranded
KW  - DNA-Binding Proteins
KW  - Electrophoresis, Gel, Pulsed-Field
KW  - Flow Cytometry
KW  - Histones
KW  - Mice
KW  - Microscopy, Confocal
KW  - Microscopy, Electron
KW  - Microscopy, Fluorescence
KW  - Mitosis
KW  - Morula
KW  - Mouse Embryonic Stem Cells
KW  - Phosphorylation
KW  - Poly(ADP-ribose) Polymerases
KW  - Rad51 Recombinase
KW  - Replication Protein A
KW  - Tumor Suppressor p53-Binding Protein 1
KW  - DNA Damage
KW  - DNA Replication
KW  - G1 Phase
KW  - G1 Phase Cell Cycle Checkpoints
TI  - A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells
TY  - journal article
ER  -