TY - GEN AU - Rio-Machín, Ana AU - Menezes, Juliane AU - Maiques-Diaz, Alba AU - Agirre, Xabier AU - Ferreira, Bibiana I AU - Acquadro, Francesco AU - Rodriguez Perales, Sandra AU - Juaristi, Karmele A AU - Alvarez, Sara AU - Cigudosa, Juan C PY - 2012 UR - https://hdl.handle.net/20.500.12105/26159 AB - The disruption of RUNX1 function is one of the main mechanisms of disease observed in hematopoietic malignancies and the description of novel genetic events that lead to a RUNX1 loss of function has been accelerated with the development of genomic... LA - eng PB - FERRATA STORTI FOUNDATION KW - AML1 KW - t(4;21)(q21;q22 KW - RUNX1 haploinsufficiency KW - megakariocytic lineage maturation TI - Abrogation of RUNX1 gene expression in de novo myelodysplastic syndrome with t(4;21)(q21;q22). TY - research article ER -