TY - GEN AU - Lafarga, Vanesa AU - Tapia, Olga AU - Sharma, Sahil AU - Bengoechea, Rocio AU - Stoecklin, Georg AU - Lafarga, Miguel AU - Berciano, Maria T PY - 2018 UR - https://hdl.handle.net/20.500.12105/26085 AB - The survival of motor neuron (SMN) protein plays an essential role in the biogenesis of spliceosomal snRNPs and the molecular assembly of Cajal bodies (CBs). Deletion of or mutations in the SMN1 gene cause spinal muscular atrophy (SMA) with... LA - eng PB - Springuer KW - CBP KW - Cajal bodies KW - HDAC inhibitor KW - Nuclear speckles KW - Protein acetylation KW - SMA KW - SMN KW - SMN complex KW - SMN interactome KW - SnRNP TI - CBP-mediated SMN acetylation modulates Cajal body biogenesis and the cytoplasmic targeting of SMN. TY - research article ER -