TY - GEN AU - de Oliveira, Jade AU - Kucharska, Ewa AU - Garcez, Michelle Lima AU - Rodrigues, Matheus Scarpatto AU - Quevedo, João AU - Moreno-Gonzalez, Ines AU - Budni, Josiane PY - 2021 DO - 10.3390/cells10102581 UR - http://hdl.handle.net/20.500.12105/18472 AB - Alzheimer's disease (AD) is the leading cause of dementia worldwide. Most AD patients develop the disease in late life, named late onset AD (LOAD). Currently, the most recognized explanation for AD pathology is the amyloid cascade hypothesis. It is... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - Alzheimer’s disease KW - Neurodegenerative disease KW - Dementia KW - Neuroinflammation KW - Inflammatory cascade KW - Systemic inflammation KW - BBB disruption KW - Anti-inflammatory effects KW - Therapy KW - Enfermedad de Alzheimer KW - Enfermedades neurodegenerativas KW - Demencia KW - Terapéutica KW - Síndrome de respuesta inflamatoria sistémica KW - Aged KW - Alzheimer Disease KW - Animals KW - Disease Models, Animal KW - Cell Death KW - Humans KW - Antirheumatic Agents KW - Systemic Inflammatory Response Syndrome TI - Inflammatory Cascade in Alzheimer's Disease Pathogenesis: A Review of Experimental Findings TY - review article ER -