TY - JOUR AU - de la Calle, Cristina AU - Lopez-Medrano, Francisco AU - Pablos, José Luis AU - Lora-Tamayo, Jaime AU - Maestro-de la Calle, Guillermo AU - Sanchez-Fernandez, Marcos AU - Fernandez-Ruiz, Mario AU - Perez-Jacoiste Asin, Maria Asunción AU - Caro-Teller, Jose Manuel AU - Garcia-Garcia, Rocio AU - Catalan, Mercedes AU - Martinez-López, Joaquín AU - Sevillano, Angel AU - Origüen, Julia AU - Ripoll, Mar AU - San Juan, Rafael AU - Lalueza, Antonio AU - de Miguel, Borja AU - Carretero, Octavio AU - Aguilar, Fernando AU - Gómez, Carlos AU - Paz-Artal, Estela AU - Bueno, Hector AU - Lumbreras, Carlos AU - Aguado, José María PY - 2021 DO - 10.1016/j.ijid.2021.02.041 SN - 1201-9712 UR - http://hdl.handle.net/20.500.12105/13431 AB - A subgroup of patients with SARS-CoV-2 infection was thought to have developed cytokine release syndrome and were treated with tocilizumab; however, a significant percentage of patients evolved. This study aimed to determine the usefulness of anakinra... LA - eng PB - Elsevier KW - SARS-CoV-2 KW - Aged KW - Antibodies, Monoclonal, Humanized KW - COVID-19 KW - Case-Control Studies KW - Cohort Studies KW - Cytokine Release Syndrome KW - Female KW - Hospital Mortality KW - Humans KW - Immunomodulation KW - Interleukin 1 Receptor Antagonist Protein KW - Male KW - Middle Aged KW - Retrospective Studies KW - Salvage Therapy KW - Spain KW - Treatment Failure KW - Treatment Outcome TI - Effectiveness of anakinra for tocilizumab-refractory severe COVID-19: A single-centre retrospective comparative study. TY - journal article ER -