TY - GEN AU - Cervera Mayor, Saint Thomas AU - Rodriguez-Martin, Carlos AU - Fernández-Tabanera, Enrique AU - Melero-Fernández de Mera, Raquel María AU - Morin, Matias AU - Fernández-Peñalver, Sergio AU - Iranzo-Martínez, Maria AU - Amhih-Cardenas, Jorge AU - Garcia-Garcia, Laura AU - Gonzalez-Gonzalez, Laura AU - Moreno-Pelayo, Miguel Angel AU - Alonso, Javier PY - 2021 DO - 10.3390/cancers13153783 SN - 2072-6694 UR - http://hdl.handle.net/20.500.12105/13321 AB - Ewing sarcoma is an aggressive bone cancer affecting children and young adults. The main molecular hallmark of Ewing sarcoma are chromosomal translocations that produce chimeric oncogenic transcription factors, the most frequent of which is the... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - CRISPR/Cas9 KW - EWSR1–FLI1 KW - Ewing sarcoma KW - Cell cycle arrest KW - Gene therapy. KW - Senescence TI - Therapeutic Potential of EWSR1-FLI1 Inactivation by CRISPR/Cas9 in Ewing Sarcoma TY - research article ER -