2024-03-28T12:12:37Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/52042022-10-06T09:16:47Zcom_20.500.12105_2145com_20.500.12105_2051com_20.500.12105_2144col_20.500.12105_2146
Repisalud
author
Peñalvo, Jose L
author
Fernandez-Friera, Leticia
author
Lopez-Melgar, Beatriz
author
Uzhova, Irina
author
Oliva, Belen
author
Fernandez-Alvira, Juan Miguel
author
Laclaustra, Martin
author
Pocock, Stuart
author
Mocoroa, Agustin
author
Mendiguren, Jose M
author
Sanz, Gines
author
Guallar, Eliseo
author
Bansilal, Sameer
author
Vedanthan, Rajesh
author
Jimenez-Borreguero, Luis J.
author
Ibáñez, Borja
author
Ordovas, Jose M
author
Fernandez-Ortiz, Antonio
author
Bueno, Hector
author
Fuster, Valentin
funder
Banco Santander
funder
Ministerio de Economía y Competitividad (España)
funder
Fundación ProCNIC
funder
National Institutes of Health (Estados Unidos)
funder
AstraZeneca
funder
Bayer Healthcare Pharmaceuticals-Bayer Pharma AG
funder
Fundación Pfizer
funder
Novartis
funder
Servier
funder
Abbott
funder
Ferrer
2017-10-30T13:15:40Z
2017-10-30T13:15:40Z
2016
J Am Coll Cardiol. 2016; 68(8):805-14
0735-1097
http://hdl.handle.net/20.500.12105/5204
27539172
10.1016/j.jacc.2016.05.080
1558-3597
Journal of the American College of Cardiology
BACKGROUND The importance of a healthy diet in relation to cardiovascular health promotion is widely recognized. Identifying specific dietary patterns related to early atherosclerosis would contribute greatly to inform effective primary prevention strategies. OBJECTIVES This study sought to quantify the association between specific dietary patterns and presence and extent of subclinical atherosclerosis in a population of asymptomatic middle-aged adults. METHODS The PESA (Progression of Early Subclinical Atherosclerosis) study enrolled 4,082 asymptomatic participants 40 to 54 years of age (mean age 45.8 years; 63\% male) to evaluate the presence of subclinical atherosclerosis in multiple vascular territories. A fundamental objective of this cohort study was to evaluate the life-style-related determinants, including diet, on atherosclerosis onset and development. We conducted a cross-sectional analysis of baseline data, including detailed information on dietary habits obtained as part of the overall life-style and risk factor assessment, as well as a complete vascular imaging study that was performed blinded to the clinical information. RESULTS Most PESA participants follow a Mediterranean (40\% of participants) or a Western (41\%) dietary pattern. A new pattern, identified among 19\% of participants, was labeled as a social-business eating pattern, characterized by a high consumption of red meat, pre-made foods, snacks, alcohol, and sugar-sweetened beverages and frequent eating-out behavior. Participants following this pattern presented a significantly worse cardiovascular risk profile and, after adjustment for risk factors, increased odds of presenting subclinical atherosclerosis (odds ratio: 1.31; 95\% confidence interval: 1.06 to 1.63) compared with participants following a Mediterranean diet. CONCLUSIONS A new social-business eating pattern, characterized by high consumption of red and processed meat, alcohol, and sugar-sweetened beverages, and by frequent snacking and eating out as part of an overall unhealthy life-style, is associated with an increased prevalence, burden, and multisite presence of subclinical atherosclerosis. (Progression of Early Subclinical Atherosclerosis [PESA]; NCT01410318) (C) 2016 by the American College of Cardiology Foundation.
eng
Cardiovascular disease
Dietary patterns
Plaque
Subclinical atherosclerosis
INTIMA-MEDIA THICKNESS
MAJOR DIETARY PATTERNS
CARDIOVASCULAR-DISEASE
SUBCLINICAL ATHEROSCLEROSIS
MEDITERRANEAN DIET
RISK
CORONARY
COHORT
METAANALYSIS
PROGRESSION
Association Between a Social-Business Eating Pattern and Early Asymptomatic Atherosclerosis
journal article
URL
https://repisalud.isciii.es/bitstream/20.500.12105/5204/1/AssociationBetweenASocial-BusinessEating_2016
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AssociationBetweenASocial-BusinessEating_2016
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AssociationBetweenASocial-BusinessEating_2016_Supp
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AssociationBetweenASocial-BusinessEating_2016.txt
URL
https://repisalud.isciii.es/bitstream/20.500.12105/5204/21/AssociationBetweenASocial-BusinessEating_2016_Supp.txt
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AssociationBetweenASocial-BusinessEating_2016_Supp.txt