2024-03-29T06:15:08Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/90852022-06-30T10:16:24Zcom_20.500.12105_2060com_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_2061
00925njm 22002777a 4500
dc
Alcazar-Fuoli, Laura
author
2016
Aspergillus fumigatus is an opportunistic pathogen and ubiquitous in the environment. In humans,
A. fumigatus can cause a wide range of infections whose symptoms are directly determined by the immunological status of the host.
1 Superficial infections are related to local trauma or overgrowth of the fungus in burns; under
occlusive dressings; after corneal trauma (keratitis); or in
the sinuses, mouth, nose, or ear canal. Allergic forms of
the diseases are caused by an exaggerated response of the
immune system to colonization of the airways with
Aspergillus
. In addition, invasive aspergillosis (IA), usu-
ally acquired through inhalation of conidia and further
fungal growth in the lung, is a systemic infection that
affects immunosuppressed patients. IA represents one of
the main cause of morbidity and mortality for infection
complications in patients with hematological malignan-
cies, hemopoietic stem cell and solid organ recipients
and patients with other immunodeficiencies.
Virulence. 2016 May 18;7(4):376-8.
2150-5594
http://hdl.handle.net/20.500.12105/9085
27029506
10.1080/21505594.2016.1169360
2150-5608
Virulence
Amino acid biosynthetic pathways as antifungal targets for fungal infections