2024-03-29T08:48:34Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/85592024-02-01T11:42:33Zcom_20.500.12105_15322com_20.500.12105_2051com_20.500.12105_2053com_20.500.12105_2052col_20.500.12105_16983col_20.500.12105_16974col_20.500.12105_16970col_20.500.12105_16964col_20.500.12105_16962col_20.500.12105_2054
00925njm 22002777a 4500
dc
Castelló Pastor, Adela
author
Boldo, Elena
author
Perez-Gomez, Beatriz
author
Lope Carvajal, Virginia
author
Altzibar, Jone M
author
Martín, Vicente
author
Castaño-Vinyals, Gemma
author
Guevara, Marcela
author
Dierssen-Sotos, Trinidad
author
Tardón, Adonina
author
Moreno, Víctor
author
Puig-Vives, Montserrat
author
Llorens-Ivorra, Cristóbal
author
Alguacil, Juan
author
Gómez-Acebo, Inés
author
Castilla Catalán, Jesús
author
Gràcia-Lavedan, Esther
author
Dávila-Batista, Verónica
author
Kogevinas, Manolis
author
Aragones, Nuria
author
Amiano, Pilar
author
Pollan-Santamaria, Marina
author
2017-09
OBJECTIVE: To externally validate the previously identified effect on breast cancer risk of the Western, Prudent and Mediterranean dietary patterns. STUDY DESIGN: MCC-Spain is a multicase-control study that collected epidemiological information on 1181 incident cases of female breast cancer and 1682 healthy controls from 10 Spanish provinces. Three dietary patterns derived in another Spanish case-control study were analysed in the MCC-Spain study. These patterns were termed Western (high intakes of fatty and sugary products and red and processed meat), Prudent (high intakes of low-fat dairy products, vegetables, fruits, whole grains and juices) and Mediterranean (high intake of fish, vegetables, legumes, boiled potatoes, fruits, olives, and vegetable oil, and a low intake of juices). Their association with breast cancer was assessed using logistic regression models with random province-specific intercepts considering an interaction with menopausal status. Risk according to tumour subtypes - based on oestrogen (ER), progesterone (PR) and human epidermal growth factor 2 (HER2) receptors (ER+/PR+ & HER2-; HER2+; ER-/PR- & HER2-) - was evaluated with multinomial regression models. MAIN OUTCOME MEASURES: Breast cancer and histological subtype. RESULTS: Our results confirm most of the associations found in the previous case-control study. A high adherence to the Western dietary pattern seems to increase breast cancer risk in both premenopausal women (OR4thvs.1stquartile (95% CI):1.68 (1.02;2.79); OR1SD-increase (95% CI):1.19 (1.02;1.40)) and postmenopausal women (OR4thvs.1stquartile(95% CI):1.48(1.07;2.05); OR1SD-increase(95% CI): 1.14 (1.01;1.29)). While high adherence to the Prudent pattern did not show any effect on breast cancer, the Mediterranean dietary pattern seemed to be protective, but only among postmenopausal women (OR4thvs.1stquartile (95% CI): 0.72 (95% CI 0.53;0.98); p-int=0.075). There were no significant differences by tumour subtype. CONCLUSION: Dietary recommendations based on a departure from the Western dietary pattern in favour of the Mediterranean diet could reduce breast cancer risk in the general population.
Maturitas. 2017 Sep;103:8-15.
03785122
http://hdl.handle.net/20.500.12105/8559
28778338
10.1016/j.maturitas.2017.06.020
1873-4111
Maturitas
Breast neoplasms
Mediterranean diet
Population attributable fraction
Prevention and control
Western diet
Adherence to the Western, Prudent and Mediterranean dietary patterns and breast cancer risk: MCC-Spain study