2024-03-28T14:25:53Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/157152023-03-28T01:01:47Zcom_20.500.12105_2145com_20.500.12105_2051com_20.500.12105_2144col_20.500.12105_2146
00925njm 22002777a 4500
dc
Han, Lei
author
Wei, Xiaoyu
author
Liu, Chuanyu
author
Volpe, Giacomo
author
Zhuang, Zhenkun
author
Zou, Xuanxuan
author
Wang, Zhifeng
author
Pan, Taotao
author
Yuan, Yue
author
Zhang, Xiao
author
Fan, Peng
author
Guo, Pengcheng
author
Lai, Yiwei
author
Lei, Ying
author
Liu, Xingyuan
author
Yu, Feng
author
Shangguan, Shuncheng
author
Lai, Guangyao
author
Deng, Qiuting
author
Liu, Ya
author
Wu, Liang
author
Shi, Quan
author
Yu, Hao
author
Huang, Yunting
author
Cheng, Mengnan
author
Xu, Jiangshan
author
Liu, Yang
author
Wang, Mingyue
author
Wang, Chunqing
author
Zhang, Yuanhang
author
Xie, Duo
author
Yang, Yunzhi
author
Yu, Yeya
author
Zheng, Huiwen
author
Wei, Yanrong
author
Huang, Fubaoqian
author
Lei, Junjie
author
Huang, Waidong
author
Zhu, Zhiyong
author
Lu, Haorong
author
Wang, Bo
author
Wei, Xiaofeng
author
Chen, Fengzhen
author
Yang, Tao
author
Du, Wensi
author
Chen, Jing
author
Xu, Shibo
author
An, Juan
author
Ward, Carl
author
Wang, Zongren
author
Pei, Zhong
author
Wong, Chi-Wai
author
Liu, Xiaolei
author
Zhang, Huafeng
author
Liu, Mingyuan
author
Qin, Baoming
author
Schambach, Axel
author
Isern, Joan
author
Feng, Liqiang
author
Liu, Yan
author
Guo, Xiangyu
author
Liu, Zhen
author
Sun, Qiang
author
Maxwell, Patrick H
author
Barker, Nick
author
Muñoz-Cánoves, Pura
author
Gu, Ying
author
Mulder, Jan
author
Uhlen, Mathias
author
Tan, Tao
author
Liu, Shiping
author
Yang, Huanming
author
Wang, Jian
author
Hou, Yong
author
Xu, Xun
author
Esteban, Miguel A
author
Liu, Longqi
author
2022-04
Studying tissue composition and function in non-human primates (NHPs) is crucial to understand the nature of our own species. Here we present a large-scale cell transcriptomic atlas that encompasses over 1 million cells from 45 tissues of the adult NHP Macaca fascicularis. This dataset provides a vast annotated resource to study a species phylogenetically close to humans. To demonstrate the utility of the atlas, we have reconstructed the cell-cell interaction networks that drive Wnt signalling across the body, mapped the distribution of receptors and co-receptors for viruses causing human infectious diseases, and intersected our data with human genetic disease orthologues to establish potential clinical associations. Our M. fascicularis cell atlas constitutes an essential reference for future studies in humans and NHPs.
Nature. 2022 Apr;604(7907):723-731
http://hdl.handle.net/20.500.12105/15715
35418686
10.1038/s41586-022-04587-3
1476-4687
Nature
Cell transcriptomic atlas of the non-human primate Macaca fascicularis.