2024-03-29T14:44:41Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/156982023-03-24T02:01:27Zcom_20.500.12105_2145com_20.500.12105_2051com_20.500.12105_2144col_20.500.12105_2146
00925njm 22002777a 4500
dc
Llorente, Vicente
author
Velarde, Pedro
author
Desco, Manuel
author
Gómez-Gaviro, María Victoria
author
2022-09-26
Neural stem cells (NSCs) are self-renewing, multipotent cells which give rise to all components of the central nervous system (CNS) during embryogenesis, but also activate in response to injury and disease and maintain a certain level of neurogenic activity throughout adulthood. This activity takes place in specialized regions of the brain, the neurovascular niches, whose main role is to control the behaviour of the CNS. In adult mammals, two main "canonical" niches have been described: The subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus. This review discusses our current understanding of the neural stem cells and their canonical niches, as well as their structure, behaviours, and role in neural disease.
Cells. 2022 Sep 26;11(19):3002
http://hdl.handle.net/20.500.12105/15698
36230964
10.3390/cells11193002
2073-4409
Cells
Current Understanding of the Neural Stem Cell Niches.