2024-03-28T19:57:32Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/152732022-12-15T02:00:34Zcom_20.500.12105_6722com_20.500.12105_2337com_20.500.12105_2336col_20.500.12105_7467
00925njm 22002777a 4500
dc
Tellez-Plaza, Maria
author
2022-12-01
The metal GWAS Initiative has as purpose to use the largest possible set of high-quality cohort studies with
data on metal and metalloid biomarkers to evaluate how levels of metal biomarkers, which are considered markers of internal dose (depending on uptake, metabolism and clearance), are influenced by genetic variation. The metal GWAS Initiative can enable: 1. The robust evaluation of genetic determinants of metal biomarkers. 2. Point to interesting biological pathways for potential metalrelated health effects, through integrative post-GWAS analysis. 3. Create the necessary structure to enable the participating cohorts to entertain large collaborative efforts to assess, in the most possible robust and reproducible way, potential metal-related health effects and associated gene-environment interactions.
Seminarios Centro Nacional de Epidemiología. 2022
http://hdl.handle.net/20.500.12105/15273
Pooled-Cohorts
Genome-Wide
Metal-GWAS Initiative
Metals
Contaminant Metals
Casdiovascular Risk Factors
Pooled-Cohorts Genome-Wide Association Study of Metals: The Metal-Gwas Initiative