2024-03-29T12:21:12Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/152372022-11-30T02:00:51Zcom_20.500.12105_2081com_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_2082
00925njm 22002777a 4500
dc
SarrĂa-Santamera, Antonio
author
Khamitova, Zaukiya
author
Gusmanov, Arnur
author
Terzic, Milan
author
Polo de Santos, Maria del Mar
author
Ortega, Miguel A
author
AsĂșnsolo, Angel
author
2022-08-20
Background: Endometriosis is a complex gynecologic disorder that has been associated with a higher risk of ovarian cancer. The purpose of this work is to determine to what extent a history of endometriosis is a risk factor for ovarian cancer in a Spanish population. Methods: A retrospective case-control study was conducted using de-identified data from the Spanish National Health System's "Primary Care Clinical Database" and "Hospital Minimum Basic Data Set" for the period 2013-2017. Multiple logistics regression analysis was conducted to determine associations between ovarian cancer and endometriosis controlled by sociodemographic characteristics and comorbidities. Results: Data from 608,980 women were analyzed, with 4505 presenting ovarian cancer. Endometriosis patients were shown to have a 2.66-fold increased risk of ovarian cancer when compared to those who did not have endometriosis by controlling age and other relevant comorbidities. Conclusions: This case-control study based on clinical administrative data has found that a history of endometriosis is independently associated with an increased risk of ovarian cancer. More research is needed to determine if a history of endometriosis affects survival results in ovarian cancer patients.
J Pers Med. 2022 Aug 20;12(8):1337.
2075-4426
http://hdl.handle.net/20.500.12105/15237
36013285
10.3390/jpm12081337
Journal of Personalized Medicine
Ovarian cancer
Risk
Sociodemographic characteristics
Endometriosis
History of Endometriosis Is Independently Associated with an Increased Risk of Ovarian Cancer