2024-03-28T22:45:04Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/143222023-10-11T10:15:15Zcom_20.500.12105_2060com_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_2061
00925njm 22002777a 4500
dc
Navero-Castillejos, Jessica
author
Benitez, Rosa
author
Torner, Nuria
author
Muñoz, José
author
Camprubí-Ferrer, Daniel
author
Peiró-Mestres, Aida
author
Sulleiro, Elena
author
Silgado, Aroa
author
Gonzalo, Verónica
author
Falgueras, Teresa
author
Alejo-Cancho, Izaskun
author
Roldán, Montserrat
author
Plasencia, Virginia
author
Albarracin, Rosa
author
Perez, Josefa
author
Navarro, Alexander
author
Calderón, Ana
author
Rubio, Rosa
author
Navarro, Mireia
author
Micó, Miguel
author
Llaberia, Jaume
author
Navarro, María
author
Barrachina, Josep
author
Vilamala, Anna
author
Martí, Carmina
author
Pulido, María Ángeles
author
Sánchez-Seco, María Paz
author
Vazquez, Ana
author
Martínez, Ana
author
Jané, Mireia
author
Martínez, Miguel Julián
author
2021-09
Dengue is the most significant arbovirus worldwide and a public health threat to non-endemic areas in which Aedes vectors are present. Autochthonous dengue transmission has been reported in several European countries in the last decade. Infected travelers from endemic regions arriving to areas colonized by Aedes albopictus in Europe need to be monitored in surveillance and control programs. We aimed to perform molecular characterization of RT-PCR-positive dengue cases detected in Catalonia, northeastern Spain, from 2013 to 2018. The basic demographic information and the geographical regions of importation were also analyzed. One-hundred four dengue cases were studied (103 imported infections and the first autochthonous case in our region). The dengue virus strains detected were serotyped and genotyped using molecular methods, and phylogenetic analyses were conducted. All four dengue serotypes were detected in travelers, including up to 10 different genotypes, reflecting the global circulation of dengue in endemic areas. The primary travel-related case of the 2018 autochthonous transmission was not identified, but the molecular analysis revealed dengue serotype 1, genotype I of Asian origin. Our results highlight the diversity of imported dengue virus strains and the role of molecular epidemiology in supporting arbovirus surveillance programs.
Viruses. 2021 Sep 23;13(10):1910.
http://hdl.handle.net/20.500.12105/14322
34696340
10.3390/v13101910
1999-4915
Viruses
Autochthonous transmission
Dengue
Molecular epidemiology
Surveillance
Molecular Characterization of Imported and Autochthonous Dengue in Northeastern Spain