2024-03-28T22:30:24Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/142072023-10-11T09:26:55Zcom_20.500.12105_15322com_20.500.12105_2051com_20.500.12105_2053com_20.500.12105_2052col_20.500.12105_16990col_20.500.12105_16983col_20.500.12105_16981col_20.500.12105_16974col_20.500.12105_16970col_20.500.12105_16968col_20.500.12105_16964col_20.500.12105_16962col_20.500.12105_16959col_20.500.12105_2054
00925njm 22002777a 4500
dc
Papantoniou, Kyriaki
author
Castaño-Vinyals, Gemma
author
Espinosa, Ana
author
Turner, Michelle C
author
Martín-Sánchez, Vicente
author
Casabonne, Delphine
author
Aragonés, Nuria
author
Gómez-Acebo, Inés
author
Ardanaz, Eva
author
Jimenez-Moleon, Jose J.
author
Amiano, Pilar
author
Molina-Barceló, Ana
author
Alguacil, Juan
author
Fernández-Tardón, Guillermo
author
Huerta, José María
author
Hernández-Segura, Natalia
author
Perez-Gomez, Beatriz
author
Llorca, Javier
author
Vidán-Alli, Juana
author
Olmedo-Requena, Rocıo
author
Gil, Leire
author
Castañon-López, Carmen
author
Pollan-Santamaria, Marina
author
Kogevinas, Manolis
author
Moreno, Victor
author
2021-06-03
Sleep duration is a novel and potentially modifiable risk factor for cancer. We evaluated the association of self-reported sleep duration and daytime napping with odds of colorectal and gastric cancer. We included 2008 incident colorectal cancer cases, 542 gastric cancer cases and 3622 frequency-matched population controls, recruited in the MCC-Spain case-control study (2008-2013). Sleep information, socio-demographic and lifestyle characteristics were obtained through personal interviews. Multivariable adjusted logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (CI) for cancer, across categories of sleep duration (≤ 5, 6, 7, 8, ≥ 9 hours/day), daytime napping frequency (naps/week) and duration (minutes/nap). Compared to 7 hours of sleep, long sleep was associated with increased odds of colorectal (OR≥9 hours: 1.59; 95%CI 1.30-1.94) and gastric cancer (OR≥9 hours: 1.95; 1.37-2.76); short sleep was associated with increased odds of gastric cancer (OR≤5 hours: 1.32; 0.93-1.88). Frequent and long daytime naps increased the odds of colorectal (OR6-7 naps/week, ≥30 min: 1.32; 1.14-1.54) and gastric cancer (OR6-7 naps/week, ≥30 min: 1.56; 1.21-2.02). Effects of short sleep and frequent long naps were stronger among participants with night shift-work history. Sleep and circadian disruption may jointly play a role in the etiology of colorectal and gastric cancer.
Sci Rep. 2021;11(1):11822.
http://hdl.handle.net/20.500.12105/14207
34083698
10.1038/s41598-021-91275-3
2045-2322
Scientific Reports
Sleep duration and napping in relation to colorectal and gastric cancer in the MCC-Spain study