2024-03-29T09:48:29Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/139162024-01-30T18:59:38Zcom_20.500.12105_15322com_20.500.12105_2051com_20.500.12105_2145com_20.500.12105_2144col_20.500.12105_16977col_20.500.12105_2146
00925njm 22002777a 4500
dc
Gómez-Talavera, Sandra
author
Fernandez-Jimenez, Rodrigo
author
Fuster, Valentin
author
Nothnagel, Nils D
author
Kouwenhoven, Marc
author
Clemence, Matthew
author
García-Lunar, Inés
author
Gómez-Rubín, María C
author
Navarro, Felipe
author
Pérez-Asenjo, Braulio
author
Fernández-Friera, Leticia
author
Calero, María J
author
Orejas, Miguel
author
Cabrera, José Ángel
author
Desco, Manuel
author
Pizarro, Gonzalo
author
Ibáñez, Borja
author
Sánchez-González, Javier
author
Nothnagel, Nils D.
author
Gómez-Rubín, María C.
author
Calero, María J.
author
Cabrera, José Ángel
author
2021-09
This study sought to clinically validate a novel 3-dimensional (3D) ultrafast cardiac magnetic resonance (CMR) protocol including cine (anatomy and function) and late gadolinium enhancement (LGE), each in a single breath-hold.
CMR is the reference tool for cardiac imaging but is time-consuming.
A protocol comprising isotropic 3D cine (Enhanced sensitivity encoding [SENSE] by Static Outer volume Subtraction [ESSOS]) and isotropic 3D LGE sequences was compared with a standard cine+LGE protocol in a prospective study of 107 patients (age 58 ± 11 years; 24% female). Left ventricular (LV) mass, volumes, and LV and right ventricular (RV) ejection fraction (LVEF, RVEF) were assessed by 3D ESSOS and 2D cine CMR. LGE (% LV) was assessed using 3D and 2D sequences.
Three-dimensional and LGE acquisitions lasted 24 and 22 s, respectively. Three-dimensional and LGE images were of good quality and allowed quantification in all cases. Mean LVEF by 3D and 2D CMR were 51 ± 12% and 52 ± 12%, respectively, with excellent intermethod agreement (intraclass correlation coefficient [ICC]: 0.96; 95% confidence interval [CI]: 0.94 to 0.97) and insignificant bias. Mean RVEF 3D and 2D CMR were 60.4 ± 5.4% and 59.7 ± 5.2%, respectively, with acceptable intermethod agreement (ICC: 0.73; 95% CI: 0.63 to 0.81) and insignificant bias. Both 2D and 3D LGE showed excellent agreement, and intraobserver and interobserver agreement were excellent for 3D LGE.
ESSOS single breath-hold 3D CMR allows accurate assessment of heart anatomy and function. Combining ESSOS with 3D LGE allows complete cardiac examination in <1 min of acquisition time. This protocol expands the indication for CMR, reduces costs, and increases patient comfort.
JACC Cardiovasc Imaging. 2021 Sep;14(9):1742-1754
1936-878X
http://hdl.handle.net/20.500.12105/13916
33865783
10.1016/j.jcmg.2021.02.031
1876-7591
JACC. Cardiovascular imaging
Clinical Validation of a 3-Dimensional Ultrafast Cardiac Magnetic Resonance Protocol Including Single Breath-Hold 3-Dimensional Sequences.