2024-03-29T06:57:00Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/119672022-11-22T14:14:10Zcom_20.500.12105_2145com_20.500.12105_2051com_20.500.12105_2144col_20.500.12105_2146
00925njm 22002777a 4500
dc
Menke, Andy
author
Guallar, Eliseo
author
Shiels, Meredith S
author
Rohrmann, Sabine
author
Basaria, Shehzad
author
Rifai, Nader
author
Nelson, William G
author
Platz, Elizabeth A
author
2008-02-23
Background: Studies investigating the association of cadmium and sex steroid hormones in men have been inconsistent, but previous studies were relatively small.
Methods: In a nationally representative sample of 1,262 men participating in the morning examination session of phase I (1998–1991) of the third National Health and Nutrition Examination Survey, creatinine corrected urinary cadmium and serum concentrations of sex steroid hormones were measured following a standardized protocol.
Results: After adjustment for age and race-ethnicity, higher cadmium levels were associated with higher levels of total testosterone, total estradiol, sex hormone-binding globulin, estimated free testosterone, and estimated free estradiol (each p-trend < 0.05). After additionally adjusting for smoking status and serum cotinine, none of the hormones maintained an association with urinary cadmium (each p-trend > 0.05).
Conclusion: Urinary cadmium levels were not associated with sex steroid hormone concentrations in a large nationally representative sample of US men.
BMC Public Health. 2008; 8:72
1471-2458
http://hdl.handle.net/20.500.12105/11967
10.1186/1471-2458-8-72
BMC Public Health
The association of urinary cadmium with sex steroid hormone concentrations in a general population sample of US adult men