2024-03-29T14:40:16Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/116482022-08-12T11:35:55Zcom_20.500.12105_2060com_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_2061
00925njm 22002777a 4500
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Medina, Narda
author
Soto-Debran, Juan Carlos
author
Seidel, Danila
author
Akyar, Isin
author
Badali, Hamid
author
Barac, Aleksandra
author
Bretagne, Stéphane
author
Cag, Yasemin
author
Cassagne, Carole
author
Castro, Carmen
author
Chakrabarti, Arunaloke
author
Dannaoui, Eric
author
Cardozo, Celia
author
Garcia-Rodriguez, Julio
author
Guitard, Juliette
author
Hamal, Petr
author
Hoenigl, Martin
author
Jagielski, Tomasz
author
Khodavaisy, Sadegh
author
Lo Cascio, Giuliana
author
Martínez-Rubio, María Carmen
author
Meletiadis, Joseph
author
Muñoz, Patricia
author
Ochman, Elżbieta
author
Peláez, Teresa
author
Perez-Ayala Balzola, Ana
author
Prattes, Juergen
author
Roilides, Emmanuel
author
Ruíz-Pérez de Pipaón, Maite
author
Stauf, Raphael
author
Steinmann, Jörg
author
Suárez-Barrenechea, Ana Isabel
author
Tejero, Rocío
author
Trovato, Laura
author
Viñuela, Lourdes
author
Wongsuk, Thanwa
author
Żak, Iwona
author
Zarrinfar, Hossein
author
Lass-Flörl, Cornelia
author
Alastruey-Izquierdo, Ana
author
2021
Invasive candidiasis remains one of the most prevalent systemic mycoses, and several studies have documented the presence of mixed yeast (MY) infections. Here, we describe the epidemiology, clinical, and microbiological characteristics of MY infections causing invasive candidiasis in a multicenter prospective study. Thirty-four centers from 14 countries participated. Samples were collected in each center between April to September 2018, and they were sent to a reference center to confirm identification by sequencing methods and to perform antifungal susceptibility testing, according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST). A total of 6895 yeast cultures were identified and MY occurred in 150 cases (2.2%). Europe accounted for the highest number of centers, with an overall MY rate of 4.2% (118 out of 2840 yeast cultures). Of 122 MY cases, the most frequent combinations were Candida albicans/C. glabrata (42, 34.4%), C. albicans/C. parapsilosis (17, 14%), and C. glabrata/C. tropicalis (8, 6.5%). All Candida isolates were susceptible to amphotericin B, 6.4% were fluconazole-resistant, and two isolates (1.6%) were echinocandin-resistant. Accurate identification of the species involved in MY infections is essential to guide treatment decisions.
J Fungi (Basel). 2021;7(1):e13.
http://hdl.handle.net/20.500.12105/11648
33383783
10.3390/jof7010013
2309-608X
Journal of fungi (Basel, Switzerland)
Candida
Chrome agar
Invasive candidiasis
Mix infections
Polymicrobial infections
Yeast
MixInYeast: A Multicenter Study on Mixed Yeast Infections