2024-03-29T14:14:07Zhttp://repisalud.isciii.es/oai/requestoai:repisalud.isciii.es:20.500.12105/108672022-11-04T10:48:25Zcom_20.500.12105_2060com_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_2061
00925njm 22002777a 4500
dc
Laursen, Christian B
author
Davidsen, Jesper Rømhild
author
Van Acker, Lander
author
Salzer, Helmut J F
author
Seidel, Danila
author
Cornely, Oliver A
author
Hoenigl, Martin
author
Hennequin, Christophe
author
Godet, Cendrine
author
Barac, Aleksandra
author
Flick, Holger
author
Munteanu, Oxana
author
Van Braeckel, Eva
author
Alastruey-Izquierdo, Ana
author
2020-06-29
Chronic pulmonary aspergillosis (CPA) is a chronic fungal infection of the lung associated with high morbidity and mortality. The CPA Research network (CPAnet) registry established in 2018 is an international multicenter collaboration aiming to improve CPA knowledge and patient care. This study's aim was to describe the data collection process and content of CPAnet registry with preliminary clinical data. In the CPAnet registry, clinical data are collected through a web-based questionnaire. Data include CPA phenotype, comorbidities, treatment, outcome, and follow-up from several international centers. An exemplary descriptive analysis was performed on 74 patients, who were registered online before April 2020. CPA patients were predominantly (72%) male, 39% had chronic obstructive pulmonary disease, and 68% had a history of smoking. Chronic cavitary pulmonary aspergillosis was the most common CPA subtype (62%). In 32 patients (52%), voriconazole was the preferred first-line therapy. The multicenter multinational CPAnet registry is a valuable approach to gather comprehensive data on a large study population and reflects real-world clinical practice rather than focusing on specific patient populations in more specialized centers. Additional CPA reference centers are being encouraged to join this promising clinical research collaboration.
J Fungi (Basel) . 2020 Jun 29;6(3):E96.
http://hdl.handle.net/20.500.12105/10867
32610566
10.3390/jof6030096
2309-608X
Journal of fungi (Basel, Switzerland)
CPAnet Registry-An International Chronic Pulmonary Aspergillosis Registry.