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dc.contributor.authorBentzon, Jacob F 
dc.contributor.authorMajesky, Mark W
dc.date.accessioned2020-05-07T10:39:15Z
dc.date.available2020-05-07T10:39:15Z
dc.date.issued2018-03
dc.identifier.citationCardiovasc Res. 2018; 114(4):492-500es_ES
dc.identifier.issn0008-6363es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/9945
dc.description.abstractAdvances in lineage-tracking techniques have provided new insights into the origins and fates of smooth muscle cells (SMCs) in atherosclerosis. Yet new tools present new challenges for data interpretation that require careful consideration of the strengths and weaknesses of the methods employed. At the same time, discoveries in other fields have introduced new perspectives on longstanding questions about steps in atherogenesis that remain poorly understood. In this article, we address both the challenges and opportunities for a better understanding of the mechanisms by which cells appearing as or deriving from SMCs accumulate in atherosclerosis.es_ES
dc.description.sponsorshipJ.F.B. was supported by research grants from the Danish Council for Independent Research (Sapere Aude II, 4004-00459B) and the Ministerio de Economia, Industria y Competitividad (MEIC; Programa RETOS, SAF2016-75580-R) with cofunding by Fondo Europeo de Desarrollo Regional (FEDER). The CNIC was supported by MEIC and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (MINECO award SEV-2015-0505). M.W.M. was supported by research grants from the National Institutes of Health (RO1-HL123650, and RO1-HL121877), the Loie Power Robinson Stem Cell & Regenerative Medicine Fund, and the Seattle Children's Research Institute, Seattle, WA.es_ES
dc.language.isoenges_ES
dc.publisherOxford University Presses_ES
dc.relation.isversionofPostprintes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.meshActins es_ES
dc.subject.meshAnimals es_ES
dc.subject.meshAtherosclerosis es_ES
dc.subject.meshBiomarkers es_ES
dc.subject.meshGene Expression Regulation, Developmental es_ES
dc.subject.meshHumans es_ES
dc.subject.meshMuscle, Smooth, Vasculares_ES
dc.subject.meshMyocytes, Smooth Musclees_ES
dc.subject.meshNeovascularization, Physiologices_ES
dc.subject.meshPhenotype es_ES
dc.subject.meshSignal Transduction es_ES
dc.subject.meshCell Differentiation es_ES
dc.subject.meshCell Lineage es_ES
dc.titleLineage tracking of origin and fate of smooth muscle cells in atherosclerosises_ES
dc.typeArtículoes_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.identifier.pubmedID29293902es_ES
dc.format.volume114es_ES
dc.format.number4es_ES
dc.format.page492-500es_ES
dc.identifier.doi10.1093/cvr/cvx251es_ES
dc.contributor.funderDanish Council for Independent Researches_ES
dc.contributor.funderMinisterio de Economía, Industria y Competitividad (España)es_ES
dc.contributor.funderEuropean Regional Development Fund (ERDF/FEDER)es_ES
dc.contributor.funderFundación ProCNICes_ES
dc.contributor.funderNational Institutes of Health (United States)es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1755-3245es_ES
dc.relation.publisherversionhttps://doi.org/10.1093/cvr/cvx251es_ES
dc.identifier.journalCardiovascular researches_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Patología Experimental de la Aterosclerosises_ES
dc.repisalud.institucionCNICes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/SEV-2015-0505es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/SAF2016-75580-Res_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
This item is licensed under a: Attribution-NonCommercial-NoDerivatives 4.0 Internacional